Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.Q328K

c.982C>A

Surrounding Variants

1 paper

NM_000245.4

p.Q328*

c.982C>T

1 paper

NM_000245.4

p.Q328insFs

c.984dupG

5 papers

NM_000245.4

p.Q328_F343delFs

c.982_1028del47

1 paper

NM_000245.4

p.A327V

c.980C>T

1 paper

NM_000245.4

p.L329fs

c.985_986fs

1 paper

NM_000245.4

p.L329fs

c.985_986fs

2 papers

NM_000245.4

p.A327T

c.979G>A

1 paper

NM_000245.4

p.A327fs

c.979_980fs

1 paper

NM_000245.4

p.A327fs

c.979_980fs

1 paper

NM_000245.4

p.G326V

c.977G>T

1 paper

NM_000245.4

p.G326R

c.976G>A

1 paper

NM_000245.4

p.G326R

c.976G>C