Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_000245.4

p.F343L

c.1029C>A

Surrounding Variants

3 papers

NM_000245.4

p.F343L

c.1029C>G

5 papers

NM_000245.4

p.G344R

c.1030G>A

4 papers

NM_000245.4

p.G344R

c.1030G>C

1 paper

NM_000245.4

p.G344W

c.1030G>T

2 papers

NM_000245.4

p.G344E

c.1031G>A

1 paper

NM_000245.4

p.G344V

c.1031G>T

3 papers

NM_000245.4

p.F343L

c.1027T>C

1 paper

NM_000245.4

p.V345M

c.1033G>A

1 paper

NM_000245.4

p.L342H

c.1025T>A

1 paper

NM_000245.4

p.L342P

c.1025T>C

1 paper

NM_000245.4

p.L342R

c.1025T>G

4 papers

NM_000245.4

p.L342I

c.1024C>A