Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_000245.4

p.V370L

c.1108G>C

Surrounding Variants

2 papers

NM_000245.4

p.V370I

c.1108G>A

1 paper

NM_000245.4

p.V370fs

c.1108_1109fs

1 paper

NM_000245.4

p.V370delFs

c.1109delT

5 papers

NM_000245.4

p.V370D

c.1109T>A

1 paper

NM_000245.4

p.Y369*

c.1107T>A

1 paper

NM_000245.4

p.V370A

c.1109T>C

1 paper

NM_000245.4

p.Y369*

c.1107T>G

1 paper

NM_000245.4

p.Y369C

c.1106A>G

1 paper

NM_000245.4

p.N371D

c.1111A>G

1 paper

NM_000245.4

p.N371Y

c.1111A>T

1 paper

NM_000245.4

p.Y369H

c.1105T>C

1 paper

NM_000245.4

p.N371T

c.1112A>C