Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.C385S

c.1154G>C

Surrounding Variants

6 papers

NM_000245.4

p.C385Y

c.1154G>A

1 paper

NM_000245.4

p.L386F

c.1156C>T

1 paper

NM_000245.4

p.R384K

c.1151G>A

3 papers

NM_000245.4

p.R384T

c.1151G>C

1 paper

NM_000245.4

p.R384*

c.1150A>T

1 paper

NM_000245.4

p.Q387*

c.1159C>T

2 papers

NM_000245.4

p.V383V

c.1149G>T

1 paper

NM_000245.4

p.Q387Q

c.1161G>A

1 paper

NM_000245.4

p.V383L

c.1147G>C

1 paper

NM_000245.4

p.V383L

c.1147G>T

1 paper

NM_000245.4

p.H388N

c.1162C>A

1 paper

NM_000245.4

p.H388H

c.1164T>C