Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.N399H

c.1195A>C

Surrounding Variants

1 paper

NM_000245.4

p.N399I

c.1196A>T

1 paper

NM_000245.4

p.F398L

c.1194T>A

1 paper

NM_000245.4

p.F398L

c.1194T>G

1 paper

NM_000245.4

p.F398L

c.1192T>C

1 paper

NM_000245.4

p.C397Y

c.1190G>A

2 papers

NM_000245.4

p.R400S

c.1200G>C

2 papers

NM_000245.4

p.R400S

c.1200G>T

1 paper

NM_000245.4

p.R400_T401Splc

c.1200+1G>A

1 paper

NM_000245.4

p.R400_T401Splc

c.1200+2T>C

2 papers

NM_000245.4

p.H396P

c.1187A>C

3 papers

NM_000245.4

p.H396R

c.1187A>G

1 paper

NM_000245.4

p.E395D

c.1185G>C