Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.C801F

c.2402G>T

Surrounding Variants

1 paper

NM_000245.4

p.C800Y

c.2399G>A

1 paper

NM_000245.4

p.T803A

c.2407A>G

2 papers

NM_000245.4

p.I799V

c.2395A>G

1 paper

NM_000245.4

p.P804P

c.2412T>C

1 paper

NM_000245.4

p.S805_L806delFs

c.2415_2416delCC

1 paper

NM_000245.4

p.S805F

c.2414C>T

2 papers

NM_000245.4

p.E797K

c.2389G>A

1 paper

NM_000245.4

p.E797Q

c.2389G>C

1 paper

NM_000245.4

p.S796L

c.2387C>T

1 paper

NM_000245.4

p.S796A

c.2386T>G

1 paper

NM_000245.4

p.N795Y

c.2383A>T

1 paper

NM_000245.4

p.Q808K

c.2422C>A