Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.D963Splc

c.2888-4T>G

Surrounding Variants

1 paper

NM_000245.4

p.D963Splc

c.2888-4T>A

1 paper

NM_000245.4

p.D963Splc

c.2888-4T>C

1 paper

NM_000245.4

p.D963Splc

c.2888-3A>C

1 paper

NM_000245.4

p.D963Splc

c.2888-2A>C

2 papers

NM_000245.4

p.D963Splc

c.2888-2A>G

8 papers

NM_000245.4

p.D963Splc

c.2888-1G>A

NM_001127500.3

p.D981Splc

c.2942-1G>A

6 papers

NM_000245.4

p.D963Splc

c.2888-1G>C

5 papers

NM_000245.4

p.D963Splc

c.2888-1G>T

1 paper

NM_001127500.3

p.D981delFs

c.2942delA

3 papers

NM_000245.4

p.D963_A973delFs

c.2888_2919del32

1 paper

NM_000245.4

p.D963_H976del0

c.2888_2926del39

1 paper

NM_000245.4

p.D963delins

c.2888delinsG