Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.V996I

c.2986G>A

Surrounding Variants

3 papers

NM_000245.4

p.S997_F1007del0

c.2990_3019del30

2 papers

NM_000245.4

p.M995_D1010delFs

c.2983_3028del46

1 paper

NM_000245.4

p.N998H

c.2992A>C

2 papers

NM_000245.4

p.E994K

c.2980G>A

1 paper

NM_000245.4

p.M995_N998delFs

c.2983_2993del11

2 papers

NM_000245.4

p.N998_Y1003delins

c.2993_3008delinsG

1 paper

NM_000245.4

p.E999_P1008del0

c.2995_3024del30

3 papers

NM_000245.4

p.T993A

c.2977A>G

1 paper

NM_000245.4

p.T993_R1004del0

c.2978_3010del33

1 paper

NM_000245.4

p.E999K

c.2995G>A

1 paper

NM_000245.4

p.E999*

c.2995G>T

1 paper

NM_000245.4

p.E999D

c.2997A>C