Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_000245.4

p.V1001_F1007del0

c.3001_3021del21

Surrounding Variants

1 paper

NM_000245.4

p.S1000T

c.2998T>A

4 papers

NM_001127500.3

p.S1018P

c.3052T>C

NM_000245.4

p.S1000P

c.2998T>C

2 papers

NM_000245.4

p.V1001_D1010delFs

c.3001_3028del28

1 paper

NM_000245.4

p.E999D

c.2997A>C

1 paper

NM_000245.4

p.E999D

c.2997A>T

1 paper

NM_000245.4

p.V1001I

c.3001G>A

2 papers

NM_000245.4

p.V1001A

c.3002T>C

NM_001127500.3

p.V1019A

c.3056T>C

1 paper

NM_000245.4

p.D1002delFs

c.3004delG

1 paper

NM_000245.4

p.V1001_P1008delins

c.3003_3023delinsTACAAGCCTATCCAAATG

1 paper

NM_000245.4

p.E999K

c.2995G>A

1 paper

NM_000245.4

p.E999*

c.2995G>T

2 papers

NM_001127500.3

p.D1020N

c.3058G>A

NM_000245.4

p.D1002N

c.3004G>A