Varaico: Literature-Extracted Genetic Variants

Gene:MET
Variant:p.A1005_D1010delFs

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain
PSIaa 519–562UCSCPlexin repeat
TIGaa 563–654UCSCIPT/TIG domain
TIGaa 657–739UCSCIPT/TIG domain
TIGaa 742–830UCSCIPT/TIG domain
PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000245.4
p.A1005_D1010delFs
c.3015_3028del14
Surrounding Variants
1 paper
NM_000245.4
p.A1005V
c.3014C>T
2 papers
NM_000245.4
p.A1005T
c.3013G>A
3 papers
NM_000245.4
p.A1005fs
c.3013_3014fs
1 paper
NM_000245.4
p.A1005fs
c.3013_3014fs
2 papers
NM_000245.4
p.T1006_D1010del0
c.3017_3028del12
1 paper
NM_000245.4
p.A1005_T1006del0
c.3013_3018del6
2 papers
NM_000245.4
p.T1006_F1007delFs
c.3018_3019delTT
1 paper
NM_000245.4
p.F1007del1
c.3019_3020delTTT
2 papers
NM_000245.4
p.R1004Q
c.3011G>A
1 paper
NM_000245.4
p.R1004_P1008del0
c.3012_3023del12
2 papers
NM_000245.4
p.R1004_E1009delFs
c.3012_3027del16
3 papers
NM_000245.4
p.R1004G
c.3010C>G
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