Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.T1006_F1007delFs

c.3018_3019delTT

Surrounding Variants

1 paper

NM_000245.4

p.F1007del1

c.3019_3020delTTT

2 papers

NM_000245.4

p.T1006_D1010del0

c.3017_3028del12

3 papers

NM_000245.4

p.F1007_D1010delFs

c.3019_3028del10

1 paper

NM_000245.4

p.F1007fs

c.3019_3020fs

1 paper

NM_000245.4

p.F1007fs

c.3019_3020fs

1 paper

NM_000245.4

p.A1005V

c.3014C>T

2 papers

NM_000245.4

p.A1005_D1010delFs

c.3015_3028del14

1 paper

NM_000245.4

p.F1007_D1010delFs

c.3021_3028del8

2 papers

NM_000245.4

p.A1005T

c.3013G>A

3 papers

NM_000245.4

p.A1005fs

c.3013_3014fs

1 paper

NM_000245.4

p.A1005fs

c.3013_3014fs

1 paper

NM_000245.4

p.P1008del1

c.3022_3023delCCA