Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.G1090C

c.3268G>T

Surrounding Variants

5 papers

NM_000245.4

p.G1090S

c.3268G>A

2 papers

NM_000245.4

p.G1090D

c.3269G>A

5 papers

NM_000245.4

p.G1090A

c.3269G>C

1 paper

NM_000245.4

p.G1090V

c.3269G>T

1 paper

NM_000245.4

p.F1089S

c.3266T>C

1 paper

NM_000245.4

p.F1089I

c.3265T>A

3 papers

NM_000245.4

p.C1091R

c.3271T>C

1 paper

NM_000245.4

p.F1089fs

c.3265_3266fs

3 papers

NM_000245.4

p.C1091Y

c.3272G>A

1 paper

NM_000245.4

p.H1088Q

c.3264T>A

1 paper

NM_000245.4

p.H1088Q

c.3264T>G

1 paper

NM_000245.4

p.H1088R

c.3263A>G