Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.L1097F

c.3291G>T

Surrounding Variants

2 papers

NM_000245.4

p.L1097F

c.3291G>C

1 paper

NM_000245.4

p.L1097S

c.3290T>C

1 paper

NM_000245.4

p.L1097V

c.3289T>G

1 paper

NM_000245.4

p.L1098F

c.3294G>C

1 paper

NM_000245.4

p.L1098F

c.3294G>T

5 papers

NM_000245.4

p.T1096S

c.3287C>G

2 papers

NM_000245.4

p.T1096I

c.3287C>T

1 paper

NM_000245.4

p.D1099N

c.3295G>A

1 paper

NM_000245.4

p.D1099H

c.3295G>C

2 papers

NM_000245.4

p.D1099G

c.3296A>G

5 papers

NM_000245.4

p.T1096S

c.3286A>T

1 paper

NM_000245.4

p.D1099V

c.3296A>T