Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.N1100D

c.3298A>G

Surrounding Variants

7 papers

NM_000245.4

p.N1100Y

c.3298A>T

NM_001127500.3

p.N1118Y

c.3352A>T

1 paper

NM_000245.4

p.N1100T

c.3299A>C

2 papers

NM_000245.4

p.N1100S

c.3299A>G

1 paper

NM_000245.4

p.D1099E

c.3297C>A

1 paper

NM_000245.4

p.D1099E

c.3297C>G

2 papers

NM_000245.4

p.D1099G

c.3296A>G

1 paper

NM_000245.4

p.D1099V

c.3296A>T

2 papers

NM_000245.4

p.D1101N

c.3301G>A

1 paper

NM_000245.4

p.D1099N

c.3295G>A

3 papers

NM_000245.4

p.D1101H

c.3301G>C

1 paper

NM_000245.4

p.D1099H

c.3295G>C

1 paper

NM_000245.4

p.D1101Y

c.3301G>T