Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.K1103N

c.3309G>T

Surrounding Variants

1 paper

NM_000245.4

p.K1103N

c.3309G>C

1 paper

NM_000245.4

p.K1103R

c.3308A>G

1 paper

NM_000245.4

p.K1104E

c.3310A>G

1 paper

NM_000245.4

p.K1104T

c.3311A>C

1 paper

NM_000245.4

p.K1103E

c.3307A>G

1 paper

NM_000245.4

p.K1104R

c.3311A>G

1 paper

NM_000245.4

p.K1104N

c.3312A>C

1 paper

NM_000245.4

p.K1104N

c.3312A>T

1 paper

NM_000245.4

p.G1102G

c.3306C>T

1 paper

NM_000245.4

p.I1105L

c.3313A>C

1 paper

NM_000245.4

p.I1105F

c.3313A>T

2 papers

NM_000245.4

p.G1102D

c.3305G>A