Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.C1107Y

c.3320G>A

Surrounding Variants

1 paper

NM_000245.4

p.C1107S

c.3320G>C

1 paper

NM_000245.4

p.C1107S

c.3319T>A

2 papers

NM_000245.4

p.C1107R

c.3319T>C

4 papers

NM_001127500.3

p.C1125G

c.3373T>G

1 paper

NM_000245.4

p.C1107W

c.3321T>G

2 papers

NM_000245.4

p.H1106Q

c.3318C>A

2 papers

NM_000245.4

p.H1106Q

c.3318C>G

1 paper

NM_000245.4

p.A1108T

c.3322G>A

1 paper

NM_000245.4

p.A1108S

c.3322G>T

1 paper

NM_000245.4

p.A1108D

c.3323C>A

1 paper

NM_000245.4

p.A1108V

c.3323C>T

2 papers

NM_000245.4

p.H1106N

c.3316C>A