Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.V1109A

c.3326T>C

Surrounding Variants

1 paper

NM_000245.4

p.V1109E

c.3326T>A

2 papers

NM_000245.4

p.V1109M

c.3325G>A

1 paper

NM_000245.4

p.V1109L

c.3325G>C

1 paper

NM_000245.4

p.V1109L

c.3325G>T

1 paper

NM_000245.4

p.K1110fs

c.3328_3329fs

1 paper

NM_000245.4

p.K1110R

c.3329A>G

1 paper

NM_000245.4

p.K1110I

c.3329A>T

1 paper

NM_000245.4

p.A1108D

c.3323C>A

1 paper

NM_000245.4

p.A1108V

c.3323C>T

1 paper

NM_000245.4

p.K1110N

c.3330A>C

1 paper

NM_000245.4

p.K1110N

c.3330A>T

1 paper

NM_000245.4

p.A1108T

c.3322G>A