Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.I1115M

c.3345C>G

Surrounding Variants

1 paper

NM_000245.4

p.T1116P

c.3346A>C

1 paper

NM_000245.4

p.T1116A

c.3346A>G

1 paper

NM_000245.4

p.I1115T

c.3344T>C

1 paper

NM_000245.4

p.I1115L

c.3343A>C

1 paper

NM_000245.4

p.I1115V

c.3343A>G

1 paper

NM_000245.4

p.I1115F

c.3343A>T

1 paper

NM_000245.4

p.D1117N

c.3349G>A

1 paper

NM_000245.4

p.D1117H

c.3349G>C

6 papers

NM_000245.4

p.D1117G

c.3350A>G

3 papers

NM_000245.4

p.I1118V

c.3352A>G

4 papers

NM_000245.4

p.I1118L

c.3352A>T

2 papers

NM_000245.4

p.I1118T

c.3353T>C