Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.F1124V

c.3370T>G

Surrounding Variants

1 paper

NM_000245.4

p.F1124I

c.3370T>A

2 papers

NM_000245.4

p.F1124L

c.3370T>C

1 paper

NM_000245.4

p.Q1123H

c.3369A>C

1 paper

NM_000245.4

p.Q1123H

c.3369A>T

2 papers

NM_000245.4

p.Q1123R

c.3368A>G

2 papers

NM_000245.4

p.F1124L

c.3372T>A

2 papers

NM_000245.4

p.F1124L

c.3372T>G

1 paper

NM_000245.4

p.Q1123K

c.3367C>A

1 paper

NM_000245.4

p.L1125V

c.3373C>G

1 paper

NM_000245.4

p.Q1123*

c.3367C>T

1 paper

NM_000245.4

p.S1122Y

c.3365C>A

1 paper

NM_000245.4

p.S1122F

c.3365C>T