Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.G1151A

c.3452G>C

Surrounding Variants

1 paper

NM_000245.4

p.G1151E

c.3452G>A

1 paper

NM_000245.4

p.G1151V

c.3452G>T

3 papers

NM_000245.4

p.G1151R

c.3451G>A

2 papers

NM_000245.4

p.G1151R

c.3451G>C

2 papers

NM_000245.4

p.G1151W

c.3451G>T

1 paper

NM_000245.4

p.S1152T

c.3454T>A

1 paper

NM_000245.4

p.S1152P

c.3454T>C

1 paper

NM_000245.4

p.S1152Y

c.3455C>A

1 paper

NM_000245.4

p.S1152F

c.3455C>T

1 paper

NM_000245.4

p.E1150K

c.3448G>A

1 paper

NM_000245.4

p.P1153A

c.3457C>G

1 paper

NM_000245.4

p.P1153S

c.3457C>T