Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.V1156A

c.3467T>C

Surrounding Variants

2 papers

NM_001127500.3

p.V1174I

c.3520G>A

NM_000245.4

p.V1156I

c.3466G>A

1 paper

NM_000245.4

p.L1157I

c.3469C>A

1 paper

NM_000245.4

p.L1157V

c.3469C>G

1 paper

NM_000245.4

p.V1155A

c.3464T>C

1 paper

NM_000245.4

p.L1157P

c.3470T>C

1 paper

NM_000245.4

p.V1155M

c.3463G>A

5 papers

NM_000245.4

p.V1155L

c.3463G>C

5 papers

NM_000245.4

p.V1155L

c.3463G>T

2 papers

NM_000245.4

p.P1158S

c.3472C>T

1 paper

NM_000245.4

p.P1158Q

c.3473C>A

1 paper

NM_000245.4

p.P1158L

c.3473C>T

1 paper

NM_000245.4

p.L1154R

c.3461T>G