Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_000245.4

p.T1173I

c.3518C>T

Surrounding Variants

1 paper

NM_000245.4

p.T1173N

c.3518C>A

1 paper

NM_000245.4

p.T1173S

c.3518C>G

1 paper

NM_000245.4

p.T1173A

c.3517A>G

1 paper

NM_000245.4

p.T1173S

c.3517A>T

2 papers

NM_000245.4

p.H1174N

c.3520C>A

2 papers

NM_000245.4

p.H1174D

c.3520C>G

1 paper

NM_000245.4

p.H1174Y

c.3520C>T

1 paper

NM_000245.4

p.E1172E

c.3516G>A

1 paper

NM_000245.4

p.E1172D

c.3516G>C

1 paper

NM_000245.4

p.E1172D

c.3516G>T

3 papers

NM_000245.4

p.H1174R

c.3521A>G

1 paper

NM_000245.4

p.E1172K

c.3514G>A