Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.I1182S

c.3545T>G

Surrounding Variants

1 paper

NM_000245.4

p.I1182T

c.3545T>C

1 paper

NM_000245.4

p.I1182L

c.3544A>C

1 paper

NM_000245.4

p.I1182V

c.3544A>G

1 paper

NM_000245.4

p.I1182M

c.3546T>G

1 paper

NM_000245.4

p.G1183S

c.3547G>A

1 paper

NM_000245.4

p.G1183C

c.3547G>T

2 papers

NM_000245.4

p.G1183D

c.3548G>A

1 paper

NM_000245.4

p.G1183V

c.3548G>T

1 paper

NM_000245.4

p.L1181P

c.3542T>C

1 paper

NM_000245.4

p.L1181R

c.3542T>G

1 paper

NM_000245.4

p.L1181I

c.3541C>A

1 paper

NM_000245.4

p.L1181V

c.3541C>G