Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.L1186I

c.3556C>A

Surrounding Variants

1 paper

NM_000245.4

p.L1186V

c.3556C>G

3 papers

NM_000245.4

p.L1186F

c.3556C>T

5 papers

NM_000245.4

p.L1186R

c.3557T>G

1 paper

NM_000245.4

p.G1185D

c.3554G>A

2 papers

NM_000245.4

p.Q1187*

c.3559C>T

1 paper

NM_000245.4

p.G1185S

c.3553G>A

1 paper

NM_000245.4

p.G1185R

c.3553G>C

1 paper

NM_000245.4

p.G1185fs

c.3553_3554fs

1 paper

NM_000245.4

p.G1185C

c.3553G>T

1 paper

NM_000245.4

p.Q1187P

c.3560A>C

1 paper

NM_000245.4

p.Q1187R

c.3560A>G

1 paper

NM_000245.4

p.F1184L

c.3552T>A