Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.A1189P

c.3565G>C

Surrounding Variants

1 paper

NM_000245.4

p.A1189T

c.3565G>A

1 paper

NM_000245.4

p.A1189S

c.3565G>T

1 paper

NM_000245.4

p.A1189V

c.3566C>T

2 papers

NM_000245.4

p.V1188I

c.3562G>A

19 papers

NM_000245.4

p.V1188L

c.3562G>C

NM_001127500.3

p.V1206L

c.3616G>C

19 papers

NM_000245.4

p.V1188L

c.3562G>T

NM_001127500.3

p.V1206L

c.3616G>T

1 paper

NM_000245.4

p.K1190R

c.3569A>G

1 paper

NM_000245.4

p.Q1187P

c.3560A>C

1 paper

NM_000245.4

p.K1190N

c.3570A>C

1 paper

NM_000245.4

p.Q1187R

c.3560A>G

1 paper

NM_000245.4

p.K1190N

c.3570A>T

2 papers

NM_000245.4

p.Q1187*

c.3559C>T