Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.L1205M

c.3613T>A

Surrounding Variants

2 papers

NM_000245.4

p.L1205V

c.3613T>G

1 paper

NM_000245.4

p.D1204E

c.3612C>A

1 paper

NM_000245.4

p.D1204E

c.3612C>G

1 paper

NM_000245.4

p.L1205S

c.3614T>C

1 paper

NM_000245.4

p.L1205F

c.3615G>C

1 paper

NM_000245.4

p.L1205F

c.3615G>T

2 papers

NM_000245.4

p.A1206T

c.3616G>A

1 paper

NM_000245.4

p.D1204N

c.3610G>A

3 papers

NM_000245.4

p.A1206S

c.3616G>T

1 paper

NM_000245.4

p.A1206V

c.3617C>T

1 paper

NM_000245.4

p.R1203K

c.3608G>A

1 paper

NM_000245.4

p.R1203T

c.3608G>C