Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.R1208K

c.3623G>A

Surrounding Variants

1 paper

NM_000245.4

p.R1208T

c.3623G>C

1 paper

NM_000245.4

p.R1208I

c.3623G>T

1 paper

NM_000245.4

p.R1208G

c.3622A>G

1 paper

NM_000245.4

p.N1209D

c.3625A>G

1 paper

NM_000245.4

p.N1209S

c.3626A>G

1 paper

NM_000245.4

p.A1207E

c.3620C>A

2 papers

NM_000245.4

p.A1207G

c.3620C>G

1 paper

NM_000245.4

p.A1207V

c.3620C>T

1 paper

NM_000245.4

p.N1209K

c.3627C>A

1 paper

NM_000245.4

p.N1209K

c.3627C>G

1 paper

NM_000245.4

p.A1207T

c.3619G>A

1 paper

NM_000245.4

p.A1207S

c.3619G>T