Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.M1211I

c.3633G>A

Surrounding Variants

1 paper

NM_000245.4

p.M1211I

c.3633G>C

1 paper

NM_000245.4

p.M1211I

c.3633G>T

1 paper

NM_000245.4

p.M1211T

c.3632T>C

3 papers

NM_000245.4

p.M1211L

c.3631A>C

2 papers

NM_000245.4

p.M1211V

c.3631A>G

3 papers

NM_000245.4

p.M1211L

c.3631A>T

1 paper

NM_000245.4

p.M1211delFs

c.3631delA

1 paper

NM_000245.4

p.C1210Y

c.3629G>A

3 papers

NM_000245.4

p.C1210S

c.3629G>C

1 paper

NM_000245.4

p.C1210F

c.3629G>T

3 papers

NM_000245.4

p.C1210S

c.3628T>A

2 papers

NM_000245.4

p.C1210R

c.3628T>C