Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.L1212R

c.3635T>G

Surrounding Variants

1 paper

NM_000245.4

p.L1212P

c.3635T>C

2 papers

NM_001127500.3

p.L1230V

c.3688C>G

NM_000245.4

p.L1212V

c.3634C>G

2 papers

NM_000245.4

p.D1213N

c.3637G>A

2 papers

NM_000245.4

p.D1213H

c.3637G>C

2 papers

NM_001127500.3

p.D1231Y

c.3691G>T

NM_000245.4

p.D1213Y

c.3637G>T

1 paper

NM_001127500.3

p.D1231A

c.3692A>C

1 paper

NM_000245.4

p.D1213V

c.3638A>T

1 paper

NM_000245.4

p.M1211Splc

c.3633-1G>T

1 paper

NM_000245.4

p.E1214K

c.3640G>A

1 paper

NM_000245.4

p.E1214Q

c.3640G>C

1 paper

NM_000245.4

p.E1214A

c.3641A>C

1 paper

NM_000245.4

p.E1214G

c.3641A>G