Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.K1215T

c.3644A>C

Surrounding Variants

1 paper

NM_000245.4

p.K1215R

c.3644A>G

1 paper

NM_000245.4

p.K1215I

c.3644A>T

2 papers

NM_000245.4

p.K1215N

c.3645A>C

1 paper

NM_000245.4

p.K1215E

c.3643A>G

2 papers

NM_000245.4

p.K1215N

c.3645A>T

1 paper

NM_000245.4

p.E1214D

c.3642A>C

1 paper

NM_000245.4

p.E1214D

c.3642A>T

1 paper

NM_000245.4

p.F1216I

c.3646T>A

2 papers

NM_000245.4

p.F1216L

c.3646T>C

1 paper

NM_000245.4

p.F1216fs

c.3646_3647fs

1 paper

NM_000245.4

p.E1214A

c.3641A>C

1 paper

NM_000245.4

p.E1214G

c.3641A>G