Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.T1217K

c.3650C>A

Surrounding Variants

1 paper

NM_000245.4

p.T1217R

c.3650C>G

1 paper

NM_000245.4

p.T1217I

c.3650C>T

1 paper

NM_000245.4

p.T1217A

c.3649A>G

2 papers

NM_000245.4

p.F1216L

c.3648C>A

2 papers

NM_000245.4

p.F1216L

c.3648C>G

1 paper

NM_000245.4

p.V1218I

c.3652G>A

1 paper

NM_000245.4

p.V1218L

c.3652G>C

1 paper

NM_000245.4

p.V1218F

c.3652G>T

1 paper

NM_000245.4

p.V1218A

c.3653T>C

1 paper

NM_000245.4

p.F1216I

c.3646T>A

2 papers

NM_000245.4

p.F1216L

c.3646T>C

1 paper

NM_000245.4

p.F1216fs

c.3646_3647fs