Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.L1225P

c.3674T>C

Surrounding Variants

1 paper

NM_000245.4

p.L1225I

c.3673C>A

1 paper

NM_000245.4

p.L1225V

c.3673C>G

1 paper

NM_000245.4

p.L1225F

c.3673C>T

1 paper

NM_000245.4

p.A1226T

c.3676G>A

1 paper

NM_000245.4

p.A1226P

c.3676G>C

1 paper

NM_000245.4

p.A1226S

c.3676G>T

1 paper

NM_000245.4

p.A1226D

c.3677C>A

1 paper

NM_000245.4

p.A1226V

c.3677C>T

1 paper

NM_000245.4

p.G1224D

c.3671G>A

1 paper

NM_000245.4

p.G1224A

c.3671G>C

2 papers

NM_000245.4

p.G1224S

c.3670G>A

1 paper

NM_000245.4

p.G1224R

c.3670G>C