Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.E1233G

c.3698A>G

Surrounding Variants

1 paper

NM_000245.4

p.E1233K

c.3697G>A

1 paper

NM_000245.4

p.E1233Q

c.3697G>C

1 paper

NM_000245.4

p.E1233*

c.3697G>T

1 paper

NM_000245.4

p.K1232N

c.3696A>C

1 paper

NM_000245.4

p.K1232N

c.3696A>T

1 paper

NM_000245.4

p.Y1234H

c.3700T>C

1 paper

NM_000245.4

p.Y1234D

c.3700T>G

1 paper

NM_000245.4

p.K1232T

c.3695A>C

4 papers

NM_000245.4

p.Y1234C

c.3701A>G

1 paper

NM_000245.4

p.K1232R

c.3695A>G

10 papers

NM_000245.4

p.Y1234F

c.3701A>T

1 paper

NM_000245.4

p.K1232E

c.3694A>G