Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.K1244N

c.3732G>T

Surrounding Variants

1 paper

NM_000245.4

p.K1244N

c.3732G>C

1 paper

NM_000245.4

p.K1244T

c.3731A>C

5 papers

NM_000245.4

p.K1244R

c.3731A>G

NM_001127500.3

p.K1262R

c.3785A>G

1 paper

NM_000245.4

p.K1244M

c.3731A>T

1 paper

NM_000245.4

p.L1245M

c.3733C>A

1 paper

NM_000245.4

p.L1245fs

c.3733_3734fs

1 paper

NM_000245.4

p.K1244insFs

c.3730_3731insC

1 paper

NM_000245.4

p.K1244E

c.3730A>G

1 paper

NM_000245.4

p.L1245Q

c.3734T>A

2 papers

NM_000245.4

p.A1243E

c.3728C>A

1 paper

NM_000245.4

p.A1243V

c.3728C>T

1 paper

NM_000245.4

p.P1246S

c.3736C>T