Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.L1252F

c.3756G>C

Surrounding Variants

1 paper

NM_000245.4

p.L1252F

c.3756G>T

2 papers

NM_000245.4

p.E1253K

c.3757G>A

1 paper

NM_000245.4

p.E1253Q

c.3757G>C

1 paper

NM_000245.4

p.L1252S

c.3755T>C

1 paper

NM_000245.4

p.E1253G

c.3758A>G

1 paper

NM_000245.4

p.E1253D

c.3759A>C

1 paper

NM_000245.4

p.E1253D

c.3759A>T

6 papers

NM_000245.4

p.S1254R

c.3760A>C

1 paper

NM_000245.4

p.S1254G

c.3760A>G

1 paper

NM_000245.4

p.A1251D

c.3752C>A

1 paper

NM_000245.4

p.A1251V

c.3752C>T

4 papers

NM_000245.4

p.A1251T

c.3751G>A