Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.T1262S

c.3784A>T

Surrounding Variants

1 paper

NM_000245.4

p.T1262_K1263ins4

c.3784_3788ins12

3 papers

NM_000245.4

p.T1262A

c.3784A>G

2 papers

NM_000245.4

p.T1262S

c.3785C>G

1 paper

NM_000245.4

p.T1262I

c.3785C>T

1 paper

NM_000245.4

p.T1261N

c.3782C>A

1 paper

NM_000245.4

p.T1261S

c.3782C>G

2 papers

NM_000245.4

p.T1261I

c.3782C>T

2 papers

NM_000245.4

p.T1261A

c.3781A>G

1 paper

NM_000245.4

p.K1263E

c.3787A>G

1 paper

NM_000245.4

p.T1261S

c.3781A>T

1 paper

NM_000245.4

p.K1263M

c.3788A>T

1 paper

NM_000245.4

p.F1260L

c.3780T>A