Varaico: Literature-Extracted Genetic Variants

Gene:METTL3
Variant:p.K459R

METTL3

96 papers

RefSeq Summary

This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryoti...

Pfam Domains

MT-A70aa 389–550UCSCMT-A70

Gene Aliases

HGNC Name

methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit

HGNC Alias Symbols

Spo8; M6A; MT-A70

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_019852.5
p.K459R
c.1376A>G
Surrounding Variants
1 paper
NM_019852.5
p.Q462E
c.1384C>G
1 paper
NM_019852.5
p.R465C
c.1393C>T
1 paper
NM_019852.5
p.R468Q
c.1403G>A
3 papers
NM_019852.5
p.R471H
c.1412G>A
1 paper
NM_019852.5
p.E506_V507Splc
c.1519-2A>G
1 paper
NM_019852.5
p.S511delFs
c.1533delA
1 paper
NM_019852.5
p.E516K
c.1546G>A
1 paper
NM_019852.5
p.R529C
c.1585C>T
1 paper
NM_019852.5
p.E532Q
c.1594G>C
1 paper
NM_019852.5
p.E532A
c.1595A>C
1 paper
NM_019852.5
p.E413D
c.1239G>T
1 paper
NM_019852.5
p.E413D
c.1239G>C
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