Varaico: Literature-Extracted Genetic Variants

Gene:METTL3
Variant:p.T74S

METTL3

96 papers

RefSeq Summary

This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryoti...

Pfam Domains

MT-A70aa 389–550UCSCMT-A70

Gene Aliases

HGNC Name

methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit

HGNC Alias Symbols

Spo8; M6A; MT-A70

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_019852.5
p.T74S
c.220A>T
Surrounding Variants
1 paper
NM_019852.5
p.T74R
c.221C>G
1 paper
NM_019852.5
p.K81*
c.241A>T
1 paper
NM_019852.5
p.T65_A66insATT
c.193_197ins9
1 paper
NM_019852.5
p.H84Y
c.250C>T
1 paper
NM_019852.5
p.G60D
c.179G>A
1 paper
NM_019852.5
p.D88G
c.263A>G
1 paper
NM_019852.5
p.S58T
c.172T>A
1 paper
NM_019852.5
p.V98M
c.292G>A
3 papers
NM_019852.5
p.S43A
c.127T>G
1 paper
NM_019852.5
p.S43P
c.127T>C
1 paper
NM_019852.5
p.A41S
c.121G>T
1 paper
NM_019852.5
p.R36P
c.107G>C
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."