Varaico: Literature-Extracted Genetic Variants

MICAL2

113 papers

RefSeq Summary

The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signalin...

Pfam Domains

FAD_binding_3aa 86–141UCSCFAD binding domain

Rossman_Micalaa 241–370UCSCMical, Rossman domain

CHaa 517–623UCSCCalponin homology (CH) domain

LIMaa 1002–1060UCSCLIM domain

bMERB_domaa 1809–1943UCSCBivalent Mical/EHBP Rab binding domain

Gene Aliases

HGNC Name

microtubule associated monooxygenase, calponin and LIM domain containing 2

HGNC Previous Symbol

MICALCL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001282663.2

p.T372I

c.1115C>T

Surrounding Variants

1 paper

NM_001282663.2

p.M368I

c.1104G>A

1 paper

NM_001282663.2

p.M368I

c.1104G>C

1 paper

NM_001282663.2

p.M368I

c.1104G>T

1 paper

NM_001282663.2

p.M368R

c.1103T>G

1 paper

NM_001282663.2

p.E378*

c.1132G>T

1 paper

NM_001282663.2

p.P364L

c.1091C>T

1 paper

NM_001282663.2

p.E385*

c.1153G>T

1 paper

NM_001282663.2

p.A357V

c.1070C>T

2 papers

NM_001282663.2

p.A388G

c.1163C>G

1 paper

NM_001282663.2

p.A388V

c.1163C>T

1 paper

NM_001282663.2

p.D355G

c.1064A>G

1 paper

NM_001282663.2

p.Q390K

c.1168C>A