Varaico: Literature-Extracted Genetic Variants

MICB

100 papers

RefSeq Summary

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T ...

Pfam Domains

MHC_Iaa 1–169UCSCClass I Histocompatibility antigen, domains alpha 1 and 2

MHC_Iaa 24–201UCSCClass I Histocompatibility antigen, domains alpha 1 and 2

C1-setaa 208–289UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

MHC class I polypeptide-related sequence B

HGNC Alias Symbol

PERB11.2

Papers

RefSeq ID

Protein change

DNA change

1–12 of 55 variants

7 papers

NM_005931.5

p.D136N

c.406G>A

6 papers

NM_005931.5

p.I121M

c.363C>G

5 papers

NM_005931.5

p.K80E

c.238A>G

5 papers

NM_005931.5

p.T212I

c.635C>T

4 papers

NM_005931.5

p.N75D

c.223A>G

3 papers

NM_005931.5

p.T383A

c.1147A>G

2 papers

NM_005931.5

p.R193*

c.577C>T

2 papers

NM_005931.5

p.R193Q

c.578G>A

2 papers

NM_005931.5

p.K196E

c.586A>G

2 papers

NM_005931.5

p.T238S

c.712A>T

2 papers

NM_005931.5

p.T238S

c.713C>G

2 papers

NM_005931.5

p.V344A

c.1031T>C