Varaico: Literature-Extracted Genetic Variants

MICB

100 papers

RefSeq Summary

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T ...

Pfam Domains

MHC_Iaa 1–169UCSCClass I Histocompatibility antigen, domains alpha 1 and 2

MHC_Iaa 24–201UCSCClass I Histocompatibility antigen, domains alpha 1 and 2

C1-setaa 208–289UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

MHC class I polypeptide-related sequence B

HGNC Alias Symbol

PERB11.2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005931.5

p.E74A

c.221A>C

Surrounding Variants

1 paper

NM_005931.5

p.E74Q

c.220G>C

4 papers

NM_005931.5

p.N75D

c.223A>G

1 paper

NM_005931.5

p.Q69fs

c.205_206fs

5 papers

NM_005931.5

p.K80E

c.238A>G

1 paper

NM_005931.5

p.K67K

c.201G>A

1 paper

NM_005931.5

p.P68delFs

c.202delC

1 paper

NM_005931.5

p.D83delFs

c.247delG

1 paper

NM_005931.5

p.D88G

c.263A>G

1 paper

NM_005931.5

p.P55S

c.163C>T

1 paper

NM_005931.5

p.D52N

c.154G>A

1 paper

NM_005931.5

p.L51V

c.151C>G

1 paper

NM_005931.5

p.F45S

c.134T>C