Varaico: Literature-Extracted Genetic Variants

MICB

100 papers

RefSeq Summary

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T ...

Pfam Domains

MHC_Iaa 1–169UCSCClass I Histocompatibility antigen, domains alpha 1 and 2

MHC_Iaa 24–201UCSCClass I Histocompatibility antigen, domains alpha 1 and 2

C1-setaa 208–289UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

MHC class I polypeptide-related sequence B

HGNC Alias Symbol

PERB11.2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005931.5

p.A200P

c.598G>C

Surrounding Variants

2 papers

NM_005931.5

p.K196E

c.586A>G

2 papers

NM_005931.5

p.R193Q

c.578G>A

2 papers

NM_005931.5

p.R193*

c.577C>T

1 paper

NM_005931.5

p.D186V

c.557A>T

1 paper

NM_005931.5

p.M183I

c.549G>A

1 paper

NM_005931.5

p.E138D

c.414G>C

7 papers

NM_005931.5

p.D136N

c.406G>A

6 papers

NM_005931.5

p.I121M

c.363C>G

1 paper

NM_005931.5

p.Q106Q

c.318G>A

1 paper

NM_005931.5

p.D105G

c.314A>G

1 paper

NM_005931.5

p.K104Q

c.310A>C

1 paper

NM_005931.5

p.D88G

c.263A>G