Varaico: Literature-Extracted Genetic Variants

MICB

100 papers

RefSeq Summary

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T ...

Pfam Domains

MHC_Iaa 1–169UCSCClass I Histocompatibility antigen, domains alpha 1 and 2

MHC_Iaa 24–201UCSCClass I Histocompatibility antigen, domains alpha 1 and 2

C1-setaa 208–289UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

MHC class I polypeptide-related sequence B

HGNC Alias Symbol

PERB11.2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005931.5

p.T238S

c.712A>T

Surrounding Variants

2 papers

NM_005931.5

p.T238S

c.713C>G

1 paper

NM_005931.5

p.R240C

c.718C>T

1 paper

NM_005931.5

p.R233W

c.697C>T

1 paper

NM_005931.5

p.S247del1

c.739_740delAGC

1 paper

NM_005931.5

p.S229G

c.685A>G

1 paper

NM_005931.5

p.H248R

c.743A>G

1 paper

NM_005931.5

p.N249D

c.745A>G

1 paper

NM_005931.5

p.E218A

c.653A>C

5 papers

NM_005931.5

p.T212I

c.635C>T

1 paper

NM_005931.5

p.T266T

c.798C>T

1 paper

NM_005931.5

p.P206R

c.617C>G

1 paper

NM_005931.5

p.Q274R

c.821A>G