Varaico: Literature-Extracted Genetic Variants

MICB

100 papers

RefSeq Summary

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T ...

Pfam Domains

MHC_Iaa 1–169UCSCClass I Histocompatibility antigen, domains alpha 1 and 2

MHC_Iaa 24–201UCSCClass I Histocompatibility antigen, domains alpha 1 and 2

C1-setaa 208–289UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

MHC class I polypeptide-related sequence B

HGNC Alias Symbol

PERB11.2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005931.5

p.V354A

c.1061T>C

Surrounding Variants

2 papers

NM_005931.5

p.V344A

c.1031T>C

1 paper

NM_005931.5

p.T377S

c.1130C>G

1 paper

NM_005931.5

p.G378G

c.1134T>C

3 papers

NM_005931.5

p.T383A

c.1147A>G

1 paper

NM_005931.5

p.G291S

c.871G>A

1 paper

NM_005931.5

p.G288R

c.862G>A

1 paper

NM_005931.5

p.Q274R

c.821A>G

1 paper

NM_005931.5

p.T266T

c.798C>T

1 paper

NM_005931.5

p.N249D

c.745A>G

1 paper

NM_005931.5

p.H248R

c.743A>G

1 paper

NM_005931.5

p.S247del1

c.739_740delAGC

1 paper

NM_005931.5

p.R240C

c.718C>T