Varaico: Literature-Extracted Genetic Variants

MID2

62 papers

RefSeq Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil reg...

Pfam Domains

zf-RING_UBOXaa 30–77UCSCRING-type zinc-finger

ANCHR-like_BBOXaa 139–181UCSCANCHR-like B-box zinc-binding domain

zf-B_boxaa 191–232UCSCB-box zinc finger

COSaa 343–394UCSCTRIM C-terminal subgroup One Signature domain

fn3aa 403–530UCSCFibronectin type III domain

SPRYaa 590–705UCSCSPRY domain

Gene Aliases

HGNC Name

midline 2

HGNC Alias Symbols

FXY2; RNF60; MRX101

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_012216.4

p.P44P

c.132T>G

Surrounding Variants

1 paper

NM_012216.4

p.L49F

c.145C>T

1 paper

NM_012216.4

p.R56C

c.166C>T

1 paper

NM_012216.4

p.S60S

c.180A>C

2 papers

NM_012216.4

p.E22G

c.65A>G

1 paper

NM_012216.4

p.A12S

c.34G>T

1 paper

NM_012216.4

p.V8M

c.22G>A

1 paper

NM_012216.4

p.G2fs

c.4_5fs

1 paper

NM_012216.4

p.R88W

c.262C>T

1 paper

NM_012216.4

p.K94E

c.280A>G

1 paper

NM_012216.4

p.R105H

c.314G>A

1 paper

NM_012216.4

p.R105R

c.315C>T

1 paper

NM_012216.4

p.S116F

c.347C>T