Varaico: Literature-Extracted Genetic Variants

MID2

62 papers

RefSeq Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil reg...

Pfam Domains

zf-RING_UBOXaa 30–77UCSCRING-type zinc-finger

ANCHR-like_BBOXaa 139–181UCSCANCHR-like B-box zinc-binding domain

zf-B_boxaa 191–232UCSCB-box zinc finger

COSaa 343–394UCSCTRIM C-terminal subgroup One Signature domain

fn3aa 403–530UCSCFibronectin type III domain

SPRYaa 590–705UCSCSPRY domain

Gene Aliases

HGNC Name

midline 2

HGNC Alias Symbols

FXY2; RNF60; MRX101

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_012216.4

p.R347Q

c.1040G>A

Surrounding Variants

2 papers

NM_012216.4

p.N343S

c.1028A>G

1 paper

NM_012216.4

p.K353E

c.1057A>G

2 papers

NM_012216.4

p.R328W

c.982C>T

2 papers

NM_012216.4

p.L312R

c.935T>G

1 paper

NM_012216.4

p.I304V

c.910A>G

1 paper

NM_012216.4

p.Q295L

c.884A>T

1 paper

NM_012216.4

p.A280G

c.839C>G

1 paper

NM_012216.4

p.V273L

c.817G>C

1 paper

NM_012216.4

p.V273L

c.817G>T