Varaico: Literature-Extracted Genetic Variants

MLKL

113 papers

RefSeq Summary

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activi...

Pfam Domains

MLKL_Naa 4–146UCSCMixed lineage kinase domain-like N-terminal domain

PK_Tyr_Ser-Thraa 209–466UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

mixed lineage kinase domain like pseudokinase

HGNC Alias Symbol

FLJ34389

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_152649.4

p.I268V

c.802A>G

Surrounding Variants

1 paper

NM_152649.4

p.R264H

c.791G>A

2 papers

NM_152649.4

p.E258A

c.773A>C

1 paper

NM_152649.4

p.E258K

c.772G>A

1 paper

NM_152649.4

p.E250A

c.749A>C

1 paper

NM_152649.4

p.K249M

c.746A>T

1 paper

NM_152649.4

p.E287K

c.859G>A

1 paper

NM_152649.4

p.L288R

c.863T>G

1 paper

NM_152649.4

p.G289R

c.865G>C

1 paper

NM_152649.4

p.G289R

c.865G>A

1 paper

NM_152649.4

p.L291P

c.872T>C

1 paper

NM_152649.4

p.E293A

c.878A>C

1 paper

NM_152649.4

p.D296A

c.887A>C