Varaico: Literature-Extracted Genetic Variants

MLKL

113 papers

RefSeq Summary

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activi...

Pfam Domains

MLKL_Naa 4–146UCSCMixed lineage kinase domain-like N-terminal domain

PK_Tyr_Ser-Thraa 209–466UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

mixed lineage kinase domain like pseudokinase

HGNC Alias Symbol

FLJ34389

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_152649.4

p.A131V

c.392C>T

Surrounding Variants

7 papers

NM_152649.4

p.S132P

c.394T>C

1 paper

NM_152649.4

p.S132C

c.395C>G

1 paper

NM_152649.4

p.I127T

c.380T>C

1 paper

NM_152649.4

p.E136Q

c.406G>C

1 paper

NM_152649.4

p.E136K

c.406G>A

1 paper

NM_152649.4

p.D137A

c.410A>C

2 papers

NM_152649.4

p.D140V

c.419A>T

1 paper

NM_152649.4

p.Q120Q

c.360A>G

1 paper

NM_152649.4

p.D142A

c.425A>C

1 paper

NM_152649.4

p.Q120E

c.358C>G

1 paper

NM_152649.4

p.Q117E

c.349C>G

3 papers

NM_152649.4

p.R146Q

c.437G>A