Varaico: Literature-Extracted Genetic Variants

MLKL

113 papers

RefSeq Summary

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activi...

Pfam Domains

MLKL_Naa 4–146UCSCMixed lineage kinase domain-like N-terminal domain

PK_Tyr_Ser-Thraa 209–466UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

mixed lineage kinase domain like pseudokinase

HGNC Alias Symbol

FLJ34389

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_152649.4

p.Q117E

c.349C>G

Surrounding Variants

1 paper

NM_152649.4

p.L116V

c.346C>G

1 paper

NM_152649.4

p.Q120E

c.358C>G

1 paper

NM_152649.4

p.Q120Q

c.360A>G

2 papers

NM_152649.4

p.E111A

c.332A>C

1 paper

NM_152649.4

p.K110E

c.328A>G

1 paper

NM_152649.4

p.D107E

c.321T>G

1 paper

NM_152649.4

p.D107E

c.321T>A

3 papers

NM_152649.4

p.D107A

c.320A>C

1 paper

NM_152649.4

p.I127T

c.380T>C

1 paper

NM_152649.4

p.R103T

c.308G>C

1 paper

NM_152649.4

p.A131V

c.392C>T

7 papers

NM_152649.4

p.S132P

c.394T>C