Varaico: Literature-Extracted Genetic Variants

MLKL

113 papers

RefSeq Summary

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activi...

Pfam Domains

MLKL_Naa 4–146UCSCMixed lineage kinase domain-like N-terminal domain

PK_Tyr_Ser-Thraa 209–466UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

mixed lineage kinase domain like pseudokinase

HGNC Alias Symbol

FLJ34389

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_152649.4

p.L45F

c.133C>T

Surrounding Variants

8 papers

NM_152649.4

p.Q48*

c.142C>T

1 paper

NM_152649.4

p.P41S

c.121C>T

1 paper

NM_152649.4

p.I39S

c.116T>G

1 paper

NM_152649.4

p.S52T

c.155G>C

1 paper

NM_152649.4

p.G37G

c.111C>A

1 paper

NM_152649.4

p.G37R

c.109G>C

1 paper

NM_152649.4

p.G37S

c.109G>A

1 paper

NM_152649.4

p.S55C

c.164C>G

1 paper

NM_152649.4

p.S55S

c.165T>A

1 paper

NM_152649.4

p.R34H

c.101G>A

1 paper

NM_152649.4

p.K57E

c.169A>G

1 paper

NM_152649.4

p.L31L

c.93G>C